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Nanobody Binding to a Conserved Epitope Promotes Norovirus Particle Disassembly

Human noroviruses are icosahedral single-stranded RNA viruses. The capsid protein is divided into shell (S) and protruding (P) domains, which are connected by a flexible hinge region. There are numerous genetically and antigenically distinct noroviruses, and the dominant strains evolve every other y...

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Bibliographic Details
Published in:J Virol
Main Authors: Koromyslova, Anna D., Hansman, Grant S.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325747/
https://ncbi.nlm.nih.gov/pubmed/25520510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03176-14
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