Positive Selection at Key Residues in the HIV Envelope Distinguishes Broad and Strain-Specific Plasma Neutralizing Antibodies

The development of HIV broadly neutralizing antibodies (bNAbs) has previously been shown to be associated with viral evolution and high levels of genetic diversity in the HIV envelope (Env) glycoprotein. However, few studies have examined Env evolution in those who fail to develop neutralization bre...

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Detalles Bibliográficos
Publicado en:J Virol
Main Authors: Mabvakure, Batsirai M., Scheepers, Cathrine, Garrett, Nigel, Abdool Karim, Salim, Williamson, Carolyn, Morris, Lynn, Moore, Penny L.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2019
Assuntos:
Pathogenesis and Immunity
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6401460/
https://ncbi.nlm.nih.gov/pubmed/30567996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01685-18
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