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Positive Selection at Key Residues in the HIV Envelope Distinguishes Broad and Strain-Specific Plasma Neutralizing Antibodies

The development of HIV broadly neutralizing antibodies (bNAbs) has previously been shown to be associated with viral evolution and high levels of genetic diversity in the HIV envelope (Env) glycoprotein. However, few studies have examined Env evolution in those who fail to develop neutralization bre...

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Dades bibliogràfiques
Publicat a:J Virol
Autors principals: Mabvakure, Batsirai M., Scheepers, Cathrine, Garrett, Nigel, Abdool Karim, Salim, Williamson, Carolyn, Morris, Lynn, Moore, Penny L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6401460/
https://ncbi.nlm.nih.gov/pubmed/30567996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01685-18
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