RNA-Binding Motif Protein 24 (RBM24) Is Involved in Pregenomic RNA Packaging by Mediating Interaction between Hepatitis B Virus Polymerase and the Epsilon Element

Encapsidation of pregenomic RNA (pgRNA) is a crucial step in hepatitis B virus (HBV) replication. Binding by viral polymerase (Pol) to the epsilon stem-loop (ε) on the 5′-terminal region (TR) of pgRNA is required for pgRNA packaging. However, the detailed mechanism is not well understood. RNA-bindin...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Yao, Yongxuan, Yang, Bo, Chen, Yingshan, Wang, Hui, Hu, Xue, Zhou, Yuan, Gao, Xiuzhu, Lu, Mengji, Niu, Junqi, Wen, Zhe, Wu, Chunchen, Chen, Xinwen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6401439/
https://ncbi.nlm.nih.gov/pubmed/30626666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02161-18
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