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COMPLEMENTARITY BETWEEN EPSILON AND PHI SEQUENCES IN PREGENOMIC RNA INFLUENCES HEPATITIS B VIRUS REPLICATION EFFICIENCY
Hepatitis B virus (HBV) replication requires the viral polymerase to reverse transcribe the 3.5-kb pregenomic viral RNA within the nucleocapsid. It has been proposed that a sequence element designated phi (φ), which is located 32 nucleotides upstream of the 3′ DR1 pregenomic RNA sequence and is comp...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2006
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1850982/ https://ncbi.nlm.nih.gov/pubmed/17056086 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2006.08.036 |
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