Parvulin 14 and Parvulin 17 Bind to HBx and cccDNA and Upregulate Hepatitis B Virus Replication from cccDNA to Virion in an HBx-Dependent Manner

The parvulin 14 (Par14) and parvulin 17 (Par17) proteins, which are both encoded by the PIN4 gene, play roles in protein folding, chromatin remodeling, DNA binding, ribosome biogenesis, and cell cycle progression. However, the effects of Par14 and Par17 on viral replication have never been explored....

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Bibliographic Details
Published in:J Virol
Main Authors: Saeed, Umar, Kim, Jumi, Piracha, Zahra Zahid, Kwon, Hyeonjoong, Jung, Jaesung, Chwae, Yong-Joon, Park, Sun, Shin, Ho-Joon, Kim, Kyongmin
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2019
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6401437/
https://ncbi.nlm.nih.gov/pubmed/30567987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01840-18
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