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Rhesus Macaque Rhadinovirus Encodes a Viral Interferon Regulatory Factor To Disrupt Promyelocytic Leukemia Nuclear Bodies and Antagonize Type I Interferon Signaling

Interferon (IFN) production and the subsequent induction of IFN-stimulated genes (ISGs) are highly effective innate strategies utilized by cells to protect against invading pathogens, including viruses. Critical components involved in this innate process are promyelocytic leukemia nuclear bodies (PM...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Springgay, Laura K., Fitzpatrick, Kristin, Park, Byung, Estep, Ryan D., Wong, Scott W.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6401433/
https://ncbi.nlm.nih.gov/pubmed/30626678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02147-18
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