Rhesus Macaque Rhadinovirus Encodes a Viral Interferon Regulatory Factor To Disrupt Promyelocytic Leukemia Nuclear Bodies and Antagonize Type I Interferon Signaling

Interferon (IFN) production and the subsequent induction of IFN-stimulated genes (ISGs) are highly effective innate strategies utilized by cells to protect against invading pathogens, including viruses. Critical components involved in this innate process are promyelocytic leukemia nuclear bodies (PM...

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Detalles Bibliográficos
Publicado en:J Virol
Main Authors: Springgay, Laura K., Fitzpatrick, Kristin, Park, Byung, Estep, Ryan D., Wong, Scott W.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2019
Assuntos:
Virus-Cell Interactions
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6401433/
https://ncbi.nlm.nih.gov/pubmed/30626678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02147-18
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