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RhoA/ROCK Signaling Modulates Lineage Commitment of Mesenchymal Stem Cells in Asthma through Lef1
RATIONALE: Mesenchymal stem cells (MSCs) are increased in the airways after allergen challenge. RhoA/ROCK signaling is critical in determining the lineage fate of MSCs in tissue repair/remodeling. OBJECTIVES: To investigate the role of RhoA/ROCK signaling in lineage commitment of MSCs during allerge...
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Pubblicato in: | J Allergy Clin Immunol |
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Autori principali: | , , , , , , , |
Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
2018
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6401351/ https://ncbi.nlm.nih.gov/pubmed/30194990 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2018.08.023 |
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