RhoA/ROCK Signaling Modulates Lineage Commitment of Mesenchymal Stem Cells in Asthma through Lef1

RATIONALE: Mesenchymal stem cells (MSCs) are increased in the airways after allergen challenge. RhoA/ROCK signaling is critical in determining the lineage fate of MSCs in tissue repair/remodeling. OBJECTIVES: To investigate the role of RhoA/ROCK signaling in lineage commitment of MSCs during allerge...

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Bibliografske podrobnosti
izdano v:J Allergy Clin Immunol
Main Authors: Ke, Xia, Do, Danh C, Li, Changjun, Zhao, Yilin, Kollarik, Marian, Fu, Qingling, Wan, Mei, Gao, Peisong
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6401351/
https://ncbi.nlm.nih.gov/pubmed/30194990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2018.08.023
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