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Allopregnanolone treatment improves plasma metabolomic profile associated with GABA metabolism in Fragile X-associated Tremor/Ataxia Syndrome: a pilot study

Currently there is no effective treatment for the Fragile X-associated Tremor/Ataxia Syndrome (FXTAS), a late-onset neurodegenerative disorder. In this pilot study, we evaluated whether allopregnanolone, a natural neurosteroid that exerts beneficial effects in neurodegenerative diseases, nervous sys...

詳細記述

保存先:
書誌詳細
出版年:Mol Neurobiol
主要な著者: Napoli, Eleonora, Schneider, Andrea, Wang, Jun Yi, Trivedi, Aditi, Carrillo, Nika Roa, Tassone, Flora, Rogawski, Michael, Hagerman, Randi J., Giulivi, Cecilia
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6401336/
https://ncbi.nlm.nih.gov/pubmed/30187385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-018-1330-3
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