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DESTINI: A deep-learning approach to contact-driven protein structure prediction

The amino acid sequence of a protein encodes the blueprint of its native structure. To predict the corresponding structural fold from the protein’s sequence is one of most challenging problems in computational biology. In this work, we introduce DESTINI (deep structural inference for proteins), a no...

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Pubblicato in:Sci Rep
Autori principali: Gao, Mu, Zhou, Hongyi, Skolnick, Jeffrey
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6401133/
https://ncbi.nlm.nih.gov/pubmed/30837676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40314-1
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