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CRISPR/Cas9 targeted CAPTURE of mammalian genomic regions for characterization by NGS
The robust detection of structural variants in mammalian genomes remains a challenge. It is particularly difficult in the case of genetically unstable Chinese hamster ovary (CHO) cell lines with only draft genome assemblies available. We explore the potential of the CRISPR/Cas9 system for the target...
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| Publié dans: | Sci Rep |
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| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6401131/ https://ncbi.nlm.nih.gov/pubmed/30837529 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-39667-4 |
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