Trimethylation of Elongation Factor-Tu by the Dual Thermoregulated Methyltransferase EftM Does Not Impact Its Canonical Function in Translation

The Pseudomonas aeruginosa methyltransferase EftM trimethylates elongation factor-Tu (EF-Tu) on lysine 5 to form a post-translational modification important for initial bacterial adherence to host epithelial cells. EftM methyltransferase activity is directly temperature regulated. The protein stabil...

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Pubblicato in:Sci Rep
Autori principali: Prezioso, Samantha M., Duong, Duc M., Kuiper, Emily G., Deng, Qiudong, Albertí, Sebastián, Conn, Graeme L., Goldberg, Joanna B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6401129/
https://ncbi.nlm.nih.gov/pubmed/30837495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-39331-x
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