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A dynamically interacting flexible loop assists oligomerisation of the Caenorhabditis elegans centriolar protein SAS-6

Centrioles are conserved organelles fundamental for the organisation of microtubules in animal cells. Oligomerisation of the spindle assembly abnormal protein 6 (SAS-6) is an essential step in the centriole assembly process and may act as trigger for the formation of these organelles. SAS-6 oligomer...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Busch, Julia M. C., Erat, Michèle C., Blank, Iris D., Musgaard, Maria, Biggin, Philip C., Vakonakis, Ioannis
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6401066/
https://ncbi.nlm.nih.gov/pubmed/30837637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40294-2
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