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A Two-Pulse Cellular Stimulation Test Elucidates Variability and Mechanisms in Signaling Pathways

Mammalian cells respond in a variable manner when provided with physiological pulses of ligand, such as low concentrations of acetylcholine present for just tens of seconds or TNFα for just tens of minutes. For a two-pulse stimulation, some cells respond to both pulses, some do not respond, and yet...

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Dades bibliogràfiques
Publicat a:Biophys J
Autors principals: Sumit, Madhuresh, Jovic, Andreja, Neubig, Richard R., Takayama, Shuichi, Linderman, Jennifer J.
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6400859/
https://ncbi.nlm.nih.gov/pubmed/30782397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.01.022
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