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Activation mechanism of ATP-sensitive K(+) channels explored with real-time nucleotide binding
The response of ATP-sensitive K(+) channels (K(ATP)) to cellular metabolism is coordinated by three classes of nucleotide binding site (NBS). We used a novel approach involving labeling of intact channels in a native, membrane environment with a non-canonical fluorescent amino acid and measurement (...
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| Publicat a: | eLife |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
eLife Sciences Publications, Ltd
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6400584/ https://ncbi.nlm.nih.gov/pubmed/30789344 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.41103 |
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