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Deubiquitinating enzyme USP30 maintains basal peroxisome abundance by regulating pexophagy

The regulation of organelle abundance is critical for cell function and survival; however, the mechanisms responsible are not fully understood. In this study, we characterize a role of the deubiquitinating enzyme USP30 in peroxisome maintenance. Peroxisomes are highly dynamic, changing in abundance...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Riccio, Victoria, Demers, Nicholas, Hua, Rong, Vissa, Miluska, Cheng, Derrick T., Strilchuk, Amy Wong, Wang, Yuqing, McQuibban, G. Angus, Kim, Peter Kijun
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6400567/
https://ncbi.nlm.nih.gov/pubmed/30700497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201804172
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