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FoxP3 and Ezh2 regulate Tfr cell suppressive function and transcriptional program
Follicular regulatory T (Tfr) cells are a regulatory T cell subset that controls antibody production by inhibiting T follicular helper (Tfh)–mediated help to B cells. Tfh and Tfr cells possess opposing functions suggesting unique programming. Here we elucidated the transcriptional program controllin...
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| Опубликовано в: : | J Exp Med |
|---|---|
| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Rockefeller University Press
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6400538/ https://ncbi.nlm.nih.gov/pubmed/30705058 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20181134 |
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