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EDA fibronectin–TLR4 axis sustains megakaryocyte expansion and inflammation in bone marrow fibrosis
The fibronectin EDA isoform (EDA FN) is instrumental in fibrogenesis but, to date, its expression and function in bone marrow (BM) fibrosis have not been explored. We found that mice constitutively expressing the EDA domain (EIIIA(+/+)), but not EDA knockout mice, are more prone to develop BM fibros...
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| Publicado no: | J Exp Med |
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| Main Authors: | , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Rockefeller University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6400533/ https://ncbi.nlm.nih.gov/pubmed/30733282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20181074 |
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