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Models to determine the kinetic mechanisms of ion-coupled transporters

With high-resolution structures available for many ion-coupled (secondary active) transporters, a major challenge for the field is to determine how coupling is accomplished. Knowledge of the kinetic mechanism of the transport reaction, which defines the binding order of substrate and co-ions, togeth...

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Pubblicato in:J Gen Physiol
Autori principali: Lolkema, Juke S., Slotboom, Dirk J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Rockefeller University Press 2019
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6400521/
https://ncbi.nlm.nih.gov/pubmed/30630873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201812055
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