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Prolyl isomerization of FAAP20 catalyzed by PIN1 regulates the Fanconi anemia pathway
The Fanconi Anemia (FA) pathway is a multi-step DNA repair process at stalled replication forks in response to DNA interstrand cross-links (ICLs). Pathological mutation of key FA genes leads to the inherited disorder FA, characterized by progressive bone marrow failure and cancer predisposition. The...
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| Publicado en: | PLoS Genet |
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| Autores principales: | , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6400411/ https://ncbi.nlm.nih.gov/pubmed/30789902 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007983 |
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