Boosting subdominant neutralizing antibody responses with a computationally designed epitope-focused immunogen

Throughout the last several decades, vaccination has been key to prevent and eradicate infectious diseases. However, many pathogens (e.g., respiratory syncytial virus [RSV], influenza, dengue, and others) have resisted vaccine development efforts, largely because of the failure to induce potent anti...

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Udgivet i:PLoS Biol
Main Authors: Sesterhenn, Fabian, Galloux, Marie, Vollers, Sabrina S., Csepregi, Lucia, Yang, Che, Descamps, Delphyne, Bonet, Jaume, Friedensohn, Simon, Gainza, Pablo, Corthésy, Patricia, Chen, Man, Rosset, Stéphane, Rameix-Welti, Marie-Anne, Éléouët, Jean-François, Reddy, Sai T., Graham, Barney S., Riffault, Sabine, Correia, Bruno E.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6400402/
https://ncbi.nlm.nih.gov/pubmed/30789898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000164
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