Activation of the D(4) dopamine receptor attenuates proliferation and migration of vascular smooth muscle cells through downregulation of AT(1a) receptor expression

Angiotensin (Ang) II has an important role in the vascular smooth muscle cell (VSMC) proliferation and migration and subsequently in the development of vascular diseases, whereas dopamine has the opposite effect. Previous studies have shown an interaction between dopamine and AT(1) receptors in the...

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Detalhes bibliográficos
Publicado no:Hypertens Res
Main Authors: Yu, Changqing, Chen, Jianghua, Guan, Weiwei, Han, Yu, Wang, Wei Eric, Wang, Xukai, Wang, Hongyong, Jose, Pedro A, Zeng, Chunyu
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6400214/
https://ncbi.nlm.nih.gov/pubmed/25832920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/hr.2015.48
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