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Dopamine D(4) receptors inhibit proliferation and migration of vascular smooth muscle cells induced by insulin via down-regulation of insulin receptor expression

Vascular smooth muscle cells (VSMCs) proliferation and migration, which are central in the development of vascular diseases, are regulated by numerous hormones and humoral factors. Activation of the insulin receptor stimulates VSMCs proliferation while dopamine receptors, via D(1) and D(3) receptors...

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Detalhes bibliográficos
Main Authors: Yu, Changqing, Wang, Zhen, Han, Yu, Liu, Yukai, Wang, Wei Eric, Chen, Caiyu, Wang, Hongyong, Jose, Pedro A, Zeng, Chunyu
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4078019/
https://ncbi.nlm.nih.gov/pubmed/24888351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2840-13-97
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