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The neoepitope landscape of breast cancer: implications for immunotherapy

BACKGROUND: Cancer immunotherapy with immune checkpoint blockade (CKB) is now standard of care for multiple cancers. The clinical response to CKB is associated with T cell immunity targeting cancer-induced mutations that generate novel HLA-binding epitopes (neoepitopes). METHODS: Here, we developed...

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書目詳細資料
發表在:BMC Cancer
Main Authors: Narang, Pooja, Chen, Meixuan, Sharma, Amit A., Anderson, Karen S., Wilson, Melissa A.
格式: Artigo
語言:Inglês
出版: BioMed Central 2019
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6399957/
https://ncbi.nlm.nih.gov/pubmed/30832597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-5402-1
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