Critical role of SREBP-1c large-VLDL pathway in environment-induced hypertriglyceridemia of apoA-V deficiency

OBJECTIVE: APOA5 variants are strongly associated with hypertriglyceridemia (HTG) as well as increased risks of cardiovascular disease and acute pancreatitis. HTG in apoA-V dysfunction often aggravates by environmental factors such as high-carbohydrate diets or aging. To date, the molecular mechanis...

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Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Takanashi, Mikio, Kimura, Takeshi, Li, Chengcheng, Tanaka, Masaki, Matsuhashi, Ako, Yoshida, Hiroki, Noda, Akari, Xu, Pengfei, Takase, Satoru, Okazaki, Sachiko, Iizuka, Yoko, Kumagai, Hidetoshi, Ikeda, Yuichi, Gotoda, Takanari, Takahashi, Manabu, Yagyu, Hiroaki, Ishibashi, Shun, Yamauchi, Toshimasa, Kadowaki, Takashi, Liang, Guosheng, Okazaki, Hiroaki
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6399473/
https://ncbi.nlm.nih.gov/pubmed/30700132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.118.311931
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