MSP-RON Signaling Is Activated in the Transition From Pancreatic Intraepithelial Neoplasia (PanIN) to Pancreatic Ductal Adenocarcinoma (PDAC)

Pancreatic ductal adenocarcinoma (PDAC) is among the deadliest epithelial malignancies and remains difficult to treat. Pancreatic intraepithelial neoplasias (PanINs) represent the majority of the pre-cancer lesions in the pancreas. The PDAC microenvironment consists of activated pancreatic stellate...

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Veröffentlicht in:Front Physiol
Hauptverfasser: Li, Ce, Morvaridi, Susan, Lam, Gloria, Chheda, Chintan, Kamata, Yoshiko, Katsumata, Makoto, Edderkaoui, Mouad, Yuan, Xiaopu, Nissen, Nicholas, Pandol, Stephen J., Wang, Qiang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Physiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6399467/
https://ncbi.nlm.nih.gov/pubmed/30863319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2019.00147
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