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Hedgehog signaling in the airway epithelium of patients with chronic obstructive pulmonary disease

Genome-wide association studies have linked gene variants of the receptor patched homolog 1 (PTCH1) with chronic obstructive pulmonary disease (COPD). However, its biological role in the disease is unclear. Our objective was to determine the expression pattern and biological role of PTCH1 in the lun...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Tam, A., Hughes, M., McNagny, K. M., Obeidat, M., Hackett, T. L., Leung, J. M., Shaipanich, T., Dorscheid, D. R., Singhera, G. K., Yang, C. W. T., Paré, P. D., Hogg, J. C., Nickle, D., Sin, D. D.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6399332/
https://ncbi.nlm.nih.gov/pubmed/30833624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40045-3
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