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The Contribution of Small Airway Obstruction to the Pathogenesis of Chronic Obstructive Pulmonary Disease

The hypothesis that the small conducting airways were the major site of obstruction to airflow in normal lungs was introduced by Rohrer in 1915 and prevailed until Weibel introduced a quantitative method of studying lung anatomy in 1963. Green repeated Rohrer's calculations using Weibels new da...

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Detalhes bibliográficos
Publicado no:Physiol Rev
Main Authors: Hogg, James C., Paré, Peter D., Hackett, Tillie-Louise
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6151481/
https://ncbi.nlm.nih.gov/pubmed/28151425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physrev.00025.2015
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