Assessing metastatic potential of breast cancer cells based on EGFR dynamics

Derailed transmembrane receptor trafficking could be a hallmark of tumorigenesis and increased tumor invasiveness, but receptor dynamics have not been used to differentiate metastatic cancer cells from less invasive ones. Using single-particle tracking techniques, we  developed a phenotyping asssay...

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Pubblicato in:Sci Rep
Autori principali: Liu, Yen-Liang, Chou, Chao-Kai, Kim, Mirae, Vasisht, Rohan, Kuo, Yu-An, Ang, Phyllis, Liu, Cong, Perillo, Evan P., Chen, Yu-An, Blocher, Katherine, Horng, Hannah, Chen, Yuan-I, Nguyen, Duc Trung, Yankeelov, Thomas E., Hung, Mien-Chie, Dunn, Andrew K., Yeh, Hsin-Chih
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6399327/
https://ncbi.nlm.nih.gov/pubmed/30833579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-37625-0
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