p300/CBP-associated factor promotes autophagic degradation of δ-catenin through acetylation and decreases prostate cancer tumorigenicity

δ-Catenin shares common binding partners with β-catenin. As acetylation and deacetylation regulate β-catenin stability, we searched for histone acetyltransferases (HATs) or histone deacetylases (HDACs) affecting δ-catenin acetylation status and protein levels. We showed that p300/CBP-associated fact...

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Vydáno v:Sci Rep
Hlavní autoři: Zhou, Rui, Yang, Yi, Park, So-Yeon, Seo, Young-Woo, Jung, Sang-Chul, Kim, Kyung Keun, Kim, Kwonseop, Kim, Hangun
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6399259/
https://ncbi.nlm.nih.gov/pubmed/30833716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40238-w
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