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DNA methylation is associated with improvement in lung function on inhaled corticosteroids in pediatric asthmatics

Asthma is the most common chronic disease in children. Inhaled corticosteroids (ICS) are the first-line treatment for asthma control, but up to one-third of children have a poor treatment response. The mechanism of ICS resistance is poorly understood, and the role of DNA methylation in ICS treatment...

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Detalhes bibliográficos
Publicado no:Pharmacogenet Genomics
Main Authors: Wang, Alberta L., Qiu, Weiliang, DeMeo, Dawn L., Raby, Benjamin A., Weiss, Scott T., Tantisira, Kelan
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6399026/
https://ncbi.nlm.nih.gov/pubmed/30640894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0000000000000366
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