Glucocorticoid Receptor Hetero-Complex Gene STIP1 Is Associated with Improved Lung Function in Asthmatics Treated with Inhaled Corticosteroids

BACKGROUND: Corticosteroids exert their anti-inflammatory action by binding and activating the intracellular the glucocorticoid receptor (GR) hetero-complex. OBJECTIVE: Evaluate the genes HSPCB, HSPCA, STIP1, HSPA8, DNAJB1, PTGES3, FKBP5, and FKBP4 on corticosteroid response. METHODS: Caucasian asth...

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Publicat a:J Allergy Clin Immunol
Autors principals: Hawkins, Gregory A., Lazarus, Ross, Smith, Richard S., Tantisira, Kelan G., Meyers, Deborah A., Peters, Stephen P., Weiss, Scott T., Bleecker, Eugene R.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4317788/
https://ncbi.nlm.nih.gov/pubmed/19254810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2009.01.049
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