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Structures in multiple conformations reveal distinct transition metal and proton pathways in an Nramp transporter

Nramp family transporters—expressed in organisms from bacteria to humans—enable uptake of essential divalent transition metals via an alternating-access mechanism that also involves proton transport. We present high-resolution structures of Deinococcus radiodurans (Dra)Nramp in multiple conformation...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:eLife
Egile Nagusiak: Bozzi, Aaron T, Zimanyi, Christina M, Nicoludis, John M, Lee, Brandon K, Zhang, Casey H, Gaudet, Rachelle
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: eLife Sciences Publications, Ltd 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6398981/
https://ncbi.nlm.nih.gov/pubmed/30714568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.41124
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