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Conserved methionine dictates substrate preference in Nramp-family divalent metal transporters
Natural resistance-associated macrophage protein (Nramp) family transporters catalyze uptake of essential divalent transition metals like iron and manganese. To discriminate against abundant competitors, the Nramp metal-binding site should favor softer transition metals, which interact either covale...
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| Gepubliceerd in: | Proc Natl Acad Sci U S A |
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| Hoofdauteurs: | , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
National Academy of Sciences
2016
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5027461/ https://ncbi.nlm.nih.gov/pubmed/27573840 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1607734113 |
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