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Claudin-4 reconstituted in unilamellar vesicles is sufficient to form tight interfaces that partition membrane proteins

Tight junctions have been hypothesized to act as molecular fences in the plasma membrane of epithelial cells, helping to form differentiated apical and basolateral domains. While this fence function is believed to arise from the interaction of four-pass transmembrane claudins, the complexity of tigh...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Belardi, Brian, Son, Sungmin, Vahey, Michael D., Wang, Jinzhi, Hou, Jianghui, Fletcher, Daniel A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6398474/
https://ncbi.nlm.nih.gov/pubmed/30209136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.221556
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