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The role of NF-κB and Elk-1 in the regulation of mouse ADAM17 expression

ADAM17 is a cell membrane metalloproteinase responsible for the release of ectodomains of numerous proteins from the cell surface. Although ADAM17 is often overexpressed in tumours and at sites of inflammation, little is known about the regulation of its expression. Here we investigate the role of N...

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Detalhes bibliográficos
Publicado no:Biol Open
Main Authors: Wawro, Karolina, Wawro, Mateusz, Strzelecka, Magdalena, Czarnek, Maria, Bereta, Joanna
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6398470/
https://ncbi.nlm.nih.gov/pubmed/30709842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.039420
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