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ADAM17 Silencing in Mouse Colon Carcinoma Cells: The Effect on Tumoricidal Cytokines and Angiogenesis

ADAM17 (a disintegrin and metalloprotease 17) is a major sheddase for numerous growth factors, cytokines, receptors, and cell adhesion molecules and is often overexpressed in malignant cells. It is generally accepted that ADAM17 promotes tumor development via activating growth factors from the EGF f...

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Bibliografiske detaljer
Main Authors: Das, Sudipta, Czarnek, Maria, Bzowska, Monika, Mężyk-Kopeć, Renata, Stalińska, Krystyna, Wyroba, Barbara, Sroka, Jolanta, Jucha, Jarosław, Deneka, Dawid, Stokłosa, Paulina, Ogonek, Justyna, Swartz, Melody A., Madeja, Zbigniew, Bereta, Joanna
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3519469/
https://ncbi.nlm.nih.gov/pubmed/23251384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050791
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