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Functional genomics screen with pooled shRNA library and gene expression profiling with extracts of Azadirachta indica identify potential pathways for therapeutic targets in head and neck squamous cell carcinoma

Tumor suppression by the extracts of Azadirachta indica (neem) works via anti-proliferation, cell cycle arrest, and apoptosis, demonstrated previously using cancer cell lines and live animal models. However, very little is known about the molecular targets and pathways that neem extracts and their a...

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Detalhes bibliográficos
Publicado no:PeerJ
Main Authors: Krishnan, Neeraja M., Katoh, Hiroto, Palve, Vinayak, Pareek, Manisha, Sato, Reiko, Ishikawa, Shumpei, Panda, Binay
Formato: Artigo
Idioma:Inglês
Publicado em: PeerJ Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6398373/
https://ncbi.nlm.nih.gov/pubmed/30842898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.6464
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