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Integrated Genomic and Proteomic Analyses Reveal Novel Mechanisms of the Methyltransferase SETD2 in Renal Cell Carcinoma Development

Clear cell renal cell carcinoma (ccRCC) is the most common type of RCC in humans. SET domain-containing 2 (SETD2), a lysine methyltransferase for histone and other proteins, has been found to be frequently lost in ccRCC. However, the mechanisms through which deficiency in SETD2 contributes to ccRCC...

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Publicado en:Mol Cell Proteomics
Main Authors: Li, Lin, Miao, Weili, Huang, Ming, Williams, Preston, Wang, Yinsheng
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Biochemistry and Molecular Biology 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6398210/
https://ncbi.nlm.nih.gov/pubmed/30487242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA118.000957
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