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Macrophage- but not monocyte-derived extracellular vesicles induce placental pro-inflammatory responses

The placenta sheds extracellular vesicles (EVs), including exosomes, into the maternal circulation. We recently demonstrated that this trafficking of EVs is bi-directional; with uptake of macrophage exosomes by the placenta inducing cytokine release. The specificity of this response is currently unk...

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Veröffentlicht in:Placenta
Hauptverfasser: Rice, Thomas F., Donaldson, Beverly, Bouqueau, Marielle, Kampmann, Beate, Holder, Beth
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6398160/
https://ncbi.nlm.nih.gov/pubmed/30213492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.placenta.2018.07.011
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