Effect of colorectal cancer-derived extracellular vesicles on the immunophenotype and cytokine secretion profile of monocytes and macrophages

BACKGROUND: Macrophages are one of the most important players in the tumor microenvironment. The polarization status of tumor associated macrophages into a pro-inflammatory type M1 or anti-inflammatory type M2 may influence cancer progression and patient survival. Extracellular vesicles (EVs) are me...

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Bibliographische Detailangaben
Veröffentlicht in:Cell Commun Signal
Hauptverfasser: Popēna, Ineta, Ābols, Artūrs, Saulīte, Līga, Pleiko, Kārlis, Zandberga, Elīna, Jēkabsons, Kaspars, Endzeliņš, Edgars, Llorente, Alicia, Linē, Aija, Riekstiņa, Una
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
Schlagworte:
Short Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5937830/
https://ncbi.nlm.nih.gov/pubmed/29690889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-018-0229-y
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