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HIV-1 envelope proteins up-regulate N(6)-methyladenosine levels of cellular RNA independently of viral replication

N(6)-methyladenosine (m(6)A) modification of HIV-1 RNA regulates viral replication and protein expression. The m(6)A modification is regulated by two groups of cellular proteins named writers and erasers that add or remove m(6)A, respectively. HIV-1 infection of CD4(+) T-cells increases m(6)A levels...

詳細記述

保存先:
書誌詳細
出版年:J Biol Chem
主要な著者: Tirumuru, Nagaraja, Wu, Li
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6398121/
https://ncbi.nlm.nih.gov/pubmed/30617182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005608
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