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N(6)-Methyladenosine–binding proteins suppress HIV-1 infectivity and viral production
The internal N(6)-methyladenosine (m(6)A) modification of cellular mRNA regulates post-transcriptional gene expression. The YTH domain family proteins (YTHDF1–3 or Y1–3) bind to m(6)A-modified cellular mRNAs and modulate their metabolism and processing, thereby affecting cellular protein translation...
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| Опубликовано в: : | J Biol Chem |
|---|---|
| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6109920/ https://ncbi.nlm.nih.gov/pubmed/29976753 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004215 |
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