Pharmacokinetics of Hydroxychloroquine in Pregnancies with Rheumatic Diseases

BACKGROUND: Hydroxychloroquine (HCQ) is an oral drug prescribed to pregnant women with rheumatic disease to reduce disease activity and prevent flares. Physiologic changes during pregnancy may substantially alter drug pharmacokinetics (PK). However, the effect of pregnancy on HCQ disposition and pot...

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Udgivet i:Clin Pharmacokinet
Main Authors: Balevic, Stephen J., Green, Thomas P., Clowse, Megan E.B., Eudy, Amanda M., Schanberg, Laura E., Cohen-Wolkowiez, Michael
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6397666/
https://ncbi.nlm.nih.gov/pubmed/30255310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-018-0712-z
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