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Pharmacokinetics of Hydroxychloroquine in Pregnancies with Rheumatic Diseases

BACKGROUND: Hydroxychloroquine (HCQ) is an oral drug prescribed to pregnant women with rheumatic disease to reduce disease activity and prevent flares. Physiologic changes during pregnancy may substantially alter drug pharmacokinetics (PK). However, the effect of pregnancy on HCQ disposition and pot...

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Détails bibliographiques
Publié dans:Clin Pharmacokinet
Auteurs principaux: Balevic, Stephen J., Green, Thomas P., Clowse, Megan E.B., Eudy, Amanda M., Schanberg, Laura E., Cohen-Wolkowiez, Michael
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6397666/
https://ncbi.nlm.nih.gov/pubmed/30255310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-018-0712-z
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