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Pharmacokinetics of Hydroxychloroquine in Pregnancies with Rheumatic Diseases

BACKGROUND: Hydroxychloroquine (HCQ) is an oral drug prescribed to pregnant women with rheumatic disease to reduce disease activity and prevent flares. Physiologic changes during pregnancy may substantially alter drug pharmacokinetics (PK). However, the effect of pregnancy on HCQ disposition and pot...

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Detalhes bibliográficos
Publicado no:Clin Pharmacokinet
Main Authors: Balevic, Stephen J., Green, Thomas P., Clowse, Megan E.B., Eudy, Amanda M., Schanberg, Laura E., Cohen-Wolkowiez, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6397666/
https://ncbi.nlm.nih.gov/pubmed/30255310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-018-0712-z
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