Role of the 12-Lipoxygenase Pathway in Diabetes Pathogenesis and Complications

12-lipoxygenase (12-LOX) is one of several enzyme isoforms responsible for the metabolism of arachidonic acid and other poly-unsaturated fatty acids to both pro- and anti-inflammatory lipid mediators. Mounting evidence has shown that 12-LOX plays a critical role in the modulation of inflammation at...

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Bibliographic Details
Published in:Pharmacol Ther
Main Authors: Dobrian, A.D., Morris, M.A., Taylor-Fishwick, D.A., Holman, T.R., Imai, Y., Mirmira, R.G., Nadler, J.L
Format: Artigo
Language:Inglês
Published: 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6397662/
https://ncbi.nlm.nih.gov/pubmed/30347209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2018.10.010
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