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Lipids and immunoinflammatory pathways of beta cell destruction
Islet inflammation contributes to beta cell demise in both type 1 and type 2 diabetes. 12-Lipoxygenase (12-LO, gene expressed as ALOX12 in human and 12-Lo in rodents in this manuscript) produces proinflammatory metabolites such as 12(S)-hydroxyeicosatetraenoic acids through dioxygenation of polyunsa...
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| 出版年: | Diabetologia |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4779407/ https://ncbi.nlm.nih.gov/pubmed/26868492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-016-3890-y |
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