Histone Modification Marks Strongly Regulate CDH1 Promoter in Prostospheres as A Model of Prostate Cancer Stem Like Cells

OBJECTIVE: Cadherin-1 (CDH1) plays an important role in the metastasis, while expression of this protein is under control of epigenetic changes on its gene promoter. Therefore we evaluated both DNA methylation (DNAmet) and histone modification marks of CDH1 in prostate cancer stem like cells (PCSLCs...

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Veröffentlicht in:Cell J
Hauptverfasser: Shokraii, Fatemeh, Moharrami, Maryam, Motamed, Nasrin, Shahhoseini, Maryam, Totonchi, Mehdi, Ezzatizadeh, Vahid, Firouzi, Javad, Khosravani, Pardis, Ebrahimi, Marzieh
Format: Artigo
Sprache:Inglês
Veröffentlicht: Royan Institute 2019
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6397603/
https://ncbi.nlm.nih.gov/pubmed/30825285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22074/cellj.2019.5702
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