Histone Modification Marks Strongly Regulate CDH1 Promoter in Prostospheres as A Model of Prostate Cancer Stem Like Cells

OBJECTIVE: Cadherin-1 (CDH1) plays an important role in the metastasis, while expression of this protein is under control of epigenetic changes on its gene promoter. Therefore we evaluated both DNA methylation (DNAmet) and histone modification marks of CDH1 in prostate cancer stem like cells (PCSLCs...

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Detalhes bibliográficos
Publicado no:Cell J
Main Authors: Shokraii, Fatemeh, Moharrami, Maryam, Motamed, Nasrin, Shahhoseini, Maryam, Totonchi, Mehdi, Ezzatizadeh, Vahid, Firouzi, Javad, Khosravani, Pardis, Ebrahimi, Marzieh
Formato: Artigo
Idioma:Inglês
Publicado em: Royan Institute 2019
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6397603/
https://ncbi.nlm.nih.gov/pubmed/30825285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22074/cellj.2019.5702
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