GDE5 inhibition accumulates intracellular glycerophosphocholine and suppresses adipogenesis at a mitotic clonal expansion stage

Mammalian glycerophosphodiesterases (GDEs) were recently shown to be involved in multiple cellular signaling pathways. This study showed that decreased GDE5 expression results in accumulation of intracellular glycerophosphocholine (GPC), showing that GDE5 is actively involved in GPC/choline metaboli...

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Bibliografski detalji
Izdano u:Am J Physiol Cell Physiol
Glavni autori: Okazaki, Yuri, Nakamura, Keishi, Takeda, Shuto, Yoshizawa, Ikumi, Yoshida, Fumiyo, Ohshima, Noriyasu, Izumi, Takashi, Klein, Janet D., Kumrungsee, Thanutchaporn, Sands, Jeff M., Yanaka, Noriyuki
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2019
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6397339/
https://ncbi.nlm.nih.gov/pubmed/30462540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00305.2018
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